@import url('https://fonts.googleapis.com/css2?family=IBM+Plex+Sans+Condensed:wght@300;400;500;600&display=swap');

:root {
  --blue: #58758a;
  --blue-dark: #405d72;
  --ink: #172635;
  --muted: #60717b;
  --line: #cdd6d8;
  --soft: #edf1f0;
  --theme-dcas: #dce8ef;
  --theme-mutagenesis: #eee0dc;
  --theme-regulatory: #dfe9e2;
  --home-section-space: 42px;
  --section-element-space: 24px;
}

body {
  font-family: "IBM Plex Sans Condensed", "Arial Narrow", Arial, sans-serif;
  background: #f8faf9;
}

.site-header {
  width: 100%;
  min-height: 74.8px;
  max-width: 1238px;
  margin: 0 auto;
  padding: 0 24px;
  display: flex;
  align-items: center;
  gap: 54px;
  background: #9eb6c9;
  box-shadow: 0 0 0 100vmax #9eb6c9;
  clip-path: inset(0 -100vmax);
}

.site-name {
  flex: 0 0 auto;
  display: flex;
  align-items: center;
  gap: 12px;
  color: #203746;
  font-size: 28.08px;
  font-weight: 500;
  letter-spacing: -.035em;
}

.site-name img {
  width: 70px;
  height: 52px;
  object-fit: contain;
  mix-blend-mode: multiply;
}

.site-header nav {
  display: flex;
  align-items: stretch;
  gap: 38px;
  margin-left: auto;
  align-self: stretch;
}

.site-header nav a,
.school-link {
  display: flex;
  align-items: center;
  color: #203746;
  font-size: 18px;
  font-weight: 500;
}

.site-header nav a {
  position: relative;
}

.site-header nav a::after {
  content: "";
  position: absolute;
  right: 0;
  bottom: 22px;
  left: 0;
  height: 2px;
  background: #36566a;
  transform: scaleX(0);
  transform-origin: left;
  transition: transform .18s ease;
}

.site-header nav a:hover::after,
.site-header nav a:focus::after,
.site-header nav a.active::after {
  transform: scaleX(1);
}

.hero-shade {
  background: linear-gradient(90deg, rgba(28, 48, 61, .86), rgba(50, 75, 89, .64) 60%, rgba(30, 52, 66, .78));
}

.hero {
  width: 100%;
  max-width: none;
  height: 258px;
  margin: 42px 0 0;
}

.hero > img {
  object-position: center 20%;
}

.hero-copy h1 {
  margin-bottom: 18px;
  font-size: 42px;
}

.hero-copy .hero-description {
  max-width: 940px;
  margin: 0;
  color: #fff;
  font-size: 20px;
  font-weight: 400;
  line-height: 1.45;
  letter-spacing: 0;
  text-transform: none;
}

.card-image {
  border-radius: 0;
}

.card-image::after {
  background: rgba(52, 81, 99, .38);
}

.section-shell {
  width: calc(100% - 48px);
}

.question-grid {
  max-width: 1100px;
  padding-top: var(--home-section-space);
  padding-bottom: var(--section-element-space);
}

.question-card p {
  font-size: 15.3px;
}

.question-card:nth-child(-n + 3) .card-image img {
  object-fit: contain;
  background: #fff;
  padding: 6px;
}

.question-card:nth-child(4) .card-image img {
  object-fit: cover;
  padding: 0;
}

.blue-button {
  background: #58758a;
}

.highlights {
  padding-top: var(--section-element-space);
  padding-bottom: var(--home-section-space);
}

.news,
.highlights {
  border-top: 2px solid var(--blue);
}

.highlight-list {
  border-top: 0;
  margin-top: 6px;
}

.news-heading {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 24px;
  margin-bottom: var(--section-element-space);
}

.news-heading h2,
.highlights > h2 {
  color: #345163;
  font-size: 31px;
  font-weight: 700;
  line-height: 1.2;
  margin: 0;
}

.news-controls {
  display: flex;
  gap: 8px;
}

.news-arrow {
  width: 42px;
  height: 42px;
  border: 1px solid #9aafbd;
  border-radius: 50%;
  background: #fff;
  color: #345163;
  font: 600 22px/1 "IBM Plex Sans Condensed", sans-serif;
  cursor: pointer;
}

.news-arrow:hover:not(:disabled),
.news-arrow:focus-visible {
  background: #58758a;
  color: #fff;
}

.news-arrow:disabled {
  opacity: .35;
  cursor: default;
}

.news-grid {
  display: grid;
  grid-auto-flow: column;
  grid-auto-columns: calc((100% - 48px) / 3);
  grid-template-columns: none;
  gap: 24px;
  overflow-x: auto;
  scroll-snap-type: x mandatory;
  scrollbar-width: thin;
  scrollbar-color: #9aafbd transparent;
  padding-bottom: 12px;
}

.news-grid article {
  display: grid;
  grid-template-columns: 166px minmax(0, 1fr);
  grid-template-rows: auto 115px;
  column-gap: 18px;
  row-gap: 6px;
  align-items: start;
  scroll-snap-align: start;
}

.news-grid time {
  grid-column: 1;
  grid-row: 1;
  justify-self: start;
}

.news-grid .placeholder-image,
.news-grid .news-image {
  grid-column: 1;
  grid-row: 2;
  width: 166px;
  height: 115px;
  margin: 0;
}

.news-grid .news-image {
  object-fit: contain;
  background: #fff;
  border: 3px solid #607f91;
}

.news-grid article:nth-child(even) .news-image {
  border-color: #8f7f83;
}

.page-banner {
  padding-top: 24px;
  padding-bottom: 24px;
}

.page-banner p {
  margin: 0 0 4px;
}

.page-banner h1 {
  font-size: 28.08px;
  line-height: 1.06;
}

.content-page {
  padding-top: var(--home-section-space);
  padding-bottom: var(--home-section-space);
}

.content-page .lead {
  max-width: 940px;
  margin-top: 0;
  font-size: 18px;
  font-weight: 400;
  line-height: 1.45;
}

.research-page .content-page {
  width: calc(100% - 48px);
  max-width: 1190px;
  padding-right: 0;
  padding-left: 0;
}

.research-page .content-page .lead {
  max-width: none;
}

.people-page .content-page {
  width: calc(100% - 48px);
  max-width: 1190px;
  padding-top: 24px;
  padding-right: 0;
  padding-left: 0;
}

.people-page .content-page .lead {
  max-width: none;
  margin-bottom: 0;
}

.people-page .people-grid {
  grid-template-columns: repeat(4, minmax(0, 1fr));
  gap: 24px;
  margin-top: 24px;
}

.people-page .person-card img,
.people-page .person-placeholder {
  width: 90%;
  height: 180px;
  margin-left: auto;
  margin-right: auto;
}

.people-page .person-card {
  border-top-color: #607f91;
}

.people-page .person-card:nth-child(even) {
  border-top-color: #8f7f83;
}

.research-page .topic-grid {
  width: 100%;
  max-width: none;
  margin: 32px auto 0;
  gap: 44px;
}

.research-page .topic-card img {
  height: 176px;
}

.theme-dcas {
  background: var(--theme-dcas);
}

.theme-mutagenesis {
  background: var(--theme-mutagenesis);
}

.theme-regulatory {
  background: var(--theme-regulatory);
}

.research-page .topic-card img.topic-image-full {
  width: 100%;
  height: auto;
  aspect-ratio: 902 / 408;
  object-fit: contain;
  background: #fff;
}

.research-page .topic-card > div {
  padding: 20px;
}

.research-page .topic-card h2 {
  margin-top: 0;
}

.publications-page {
  width: calc(100% - 48px);
  max-width: 1190px;
  padding-top: 24px;
  padding-right: 0;
  padding-left: 0;
}

.publication-note {
  margin: 0 0 18px;
  color: var(--muted);
  font-size: 15px;
}

.publication-theme-key {
  display: flex;
  flex-wrap: wrap;
  gap: 10px 18px;
  margin-bottom: 12px;
  font-size: 14px;
}

.publication-theme-key span {
  display: inline-flex;
  align-items: center;
  gap: 7px;
  background: transparent;
}

.publication-theme-key i {
  width: 15px;
  height: 15px;
  border: 1px solid rgba(23, 38, 53, .16);
}

.publication-theme-key .theme-dcas i {
  background: var(--theme-dcas);
}

.publication-theme-key .theme-mutagenesis i {
  background: var(--theme-mutagenesis);
}

.publication-theme-key .theme-regulatory i {
  background: var(--theme-regulatory);
}

.publication-section + .publication-section {
  margin-top: 42px;
}

.publication-section h2 {
  margin: 0 0 16px;
  color: #345163;
  font-size: 24px;
}

.full-publication-list {
  margin: 0;
  padding-left: 2.25rem;
  border-top: 2px solid var(--blue);
}

.full-publication-list li {
  --publication-theme-bg: #fff;
  padding: 15px 8px 15px 4px;
  border-bottom: 1px solid var(--line);
  background: var(--publication-theme-bg);
  box-shadow: -2.25rem 0 0 var(--publication-theme-bg);
  font-size: 16px;
  line-height: 1.45;
}

.preprint-list li:nth-child(-n + 3) {
  --publication-theme-bg: var(--theme-dcas);
}

.preprint-list li:nth-child(4),
.peer-reviewed-list li {
  --publication-theme-bg: var(--theme-regulatory);
}

.peer-reviewed-list li:is(:nth-child(1), :nth-child(2), :nth-child(3), :nth-child(6), :nth-child(9), :nth-child(12), :nth-child(17), :nth-child(18)) {
  --publication-theme-bg: var(--theme-mutagenesis);
}

.full-publication-list li::marker {
  color: var(--blue-dark);
  font-weight: 600;
}

.full-publication-list a {
  color: var(--blue-dark);
  text-decoration: underline;
  text-underline-offset: 2px;
}

.news-grid h3 {
  grid-column: 2;
  grid-row: 2;
  font-size: 16.5px;
  font-weight: 400;
  line-height: 1.35;
  margin: 0;
}

@media (max-width: 900px) {
  .news-grid {
    grid-auto-columns: calc((100% - 24px) / 2);
  }
}

@media (max-width: 600px) {
  .news-grid {
    grid-auto-columns: 86%;
  }
}

.highlight-list article {
  display: grid;
  grid-template-columns: 144px 1fr;
  gap: 24px;
  align-items: center;
  padding: 18px 0;
}

.highlight-list article > img {
  width: 144px;
  height: 100px;
  object-fit: cover;
  background: #edf1f0;
}

.highlight-list article > img.diagram-placeholder {
  object-fit: contain;
  padding: 8px;
  background: #fff;
}

.highlight-copy h3 a:hover,
.highlight-copy h3 a:focus-visible {
  color: #58758a;
  text-decoration: underline;
}

.news {
  padding-top: var(--section-element-space);
  padding-bottom: var(--section-element-space);
}

.placeholder-image {
  background: linear-gradient(135deg, #536f82, #9ab0b5);
}

.placeholder-image.alternate {
  background: linear-gradient(135deg, #677d91, #b6a6a0);
}

footer {
  background: #334955;
}

.footer-brand {
  display: flex;
  align-items: center;
  gap: 24px;
}

.footer-brand > p {
  margin: 0;
}

.footer-title {
  display: flex;
  align-items: center;
  gap: 12px;
}

.footer-title a {
  display: block;
  flex: 0 0 auto;
}

.footer-title img {
  width: 56px;
  height: 36px;
  padding: 3px;
  object-fit: contain;
  background: #fff;
}

.footer-title a:nth-child(2) img {
  width: 68px;
}

.footer-brand p a {
  color: inherit;
}

.footer-brand p a:hover,
.footer-brand p a:focus,
.footer-links a:hover,
.footer-links a:focus {
  text-decoration: underline;
}

.contact-details a {
  color: var(--header-blue-dark);
  text-decoration: underline;
}

.contact-page .content-page {
  width: calc(100% - 48px);
  max-width: 1190px;
}

.contact-grid {
  grid-template-columns: 2fr 1fr;
}

.map-card {
  margin: 0;
  padding: 0;
  overflow: hidden;
}

.map-card img {
  width: 100%;
  height: auto;
  min-height: 240px;
  object-fit: contain;
  background: #fff;
}

.map-card figcaption {
  padding: 12px 16px;
  font-size: 16px;
}

.map-card figcaption a {
  color: var(--header-blue-dark);
  text-decoration: underline;
}

@media (max-width: 900px) {
  .section-shell,
  .section-shell:not(.question-grid),
  .question-grid {
    padding-right: 0;
    padding-left: 0;
  }

  .site-header {
    padding: 0 24px;
    gap: 28px;
  }

  .site-header nav {
    gap: 24px;
  }

  .people-page .people-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

}

@media (max-width: 650px) {
  .contact-grid {
    grid-template-columns: 1fr;
  }

  .site-header {
    min-height: 0;
    padding: 22px 20px 16px;
    flex-wrap: wrap;
  }

  .footer-brand {
    align-items: flex-start;
    flex-direction: column;
  }

  .people-page .people-grid {
    grid-template-columns: 1fr;
  }

  .site-name {
    width: 100%;
    font-size: 26px;
  }

  .site-header nav {
    width: 100%;
    gap: 0;
    justify-content: space-between;
  }

  .site-header nav a {
    padding: 8px 0 4px;
    font-size: 16.8px;
  }

  .site-header nav a::after {
    bottom: 0;
  }

  .hero {
    height: 340px;
  }

  .hero-copy h1 {
    font-size: 35px;
  }

  .hero-copy .hero-description {
    font-size: 18px;
  }

  .page-banner h1 {
    font-size: 26px;
  }

  .content-page .lead {
    font-size: 16.8px;
  }

}